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Application notes
Himac Application No.157 – The Easy Virus Detection using Ultracentrifuge and Electron Microscope

Himac CS-FNX series and CSI 50NX micro ultracentrifuges for separation / SI 00AT3 fixed angle rotor

The detection of norovirus is most famous in the virus detection using ultracentrifuge and electron microscope. Norovirus (formerly NorwaIk agent") is an RNA virus (taxonomic family CaIiciviridae) that caused approximately 90 % Of epidemic nonbacterial outbreaks of gastroenteritis around the world. Norovirus has approximately 7,500 bases and its size is 30- 38 nm of a regular icosahedron, Norovirus is rapidly inactivated by either sufficient heating or by chlorine-based disinfectants, but the virus is less susceptible to alcohols and detergents, because it does not have a lipid envelope.

This application describes the new technique that can perform the detection of the norovirus in the sample of only 100uL



TEM Image of the Norovirus



Reference
1) himac APPLICATION No.157 (Dec 2012).

Product information Himac Ultracentrifuge

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